Biomarker Research Laboratory


The TRIBE Biomarker Laboratory (TBL) promotes discovery and analysis of novel biomarkers in human bio specimens for translational research studies. The laboratory utilizes a variety of instrumentation for sample analysis including a compound light microscope, Siemens Diagnostics Clinitek Status+ Urinalysis Analyzer, IDEXX SediVue DX automated urine microscope, BioTek Synergy HT muli-mode microplate reader for ELISA analysis, and Meso Scale Discovery (MSD) MESO QuickPlex SQ 120 instrument for electrochemiluminescence detection of biomarkers in singleplex and multiplex assay formats. Additionally, the laboratory operates an automated Rx Daytona clinical chemistry analyzer from Randox Laboratories capable of measuring electrolytes, creatinine, albumin, cystatin C, and a variety of other analytes listed below. The laboratory employs Sorvall legend X1R bench top centrifuges, refrigerators, and freezers (-20°C and -80°C) for processing and temporary storage of samples and reagents. Long term sample storage is also offered through our biorepository.

Siemens Diagnostics Clinitek Status+ urinalysis analyzer
  • Routine urine tests
    • albumin, bilirubin, creatinine, glucose, ketone, leukocytes, nitrite, pH, protein, specific gravity, and urobilinogen
  • Kidney disease test
    • albumin-to-creatinine ratio
  • Full list of Siemens analytes
    • Siemens Diagnostics Clinitek Status+ urinalysis analyzer
Randox RX Daytona -Automated clinical chemistry analyzer
  • Albumin
    • Urine, blood
  • ALT
    • Serum, Plasma (EDTA or heparinized)
  • AST
    • Serum, Plasma (EDTA or heparinized)
  • Creatine Kinase
    • Serum, Plasma (EDTA or heparinized)
  • CRP/hs-CRP
    • Serum, Plasma (Na-EDTA, K=EDTA, Na-Heparin, Li-Heparin, Citrate)
  • Creatinine
    • Serum, Plasma (heparinized), Urine
  • Urea
    • Serum, Plasma (heparinized but not ammonium heparinate)
  • L-ɣ-Glutamyltransferase (GGT)
    • Serum, Plasma (EDTA, Li-Heparin)
  • Cystatin C
    • Serum, Plasma (Lithium heparin or potassium EDTA), Urine
  • Myoglobin
    • Serum
  • Full list of Randox analytes
    • Randox RX Daytona -Automated clinical chemistry analyzer
MESO QuickPlex SQ 120 instrument assays
  • Custom 3-plex (IL-18, KIM-1, MCP-1)
    • Serum, Plasma (EDTA), Urine
  • Custom 2-plex (YKL-40, NGAL/LCN2)
    • Serum, Plasma (EDTA), Urine
  • Custom 2-plex (Ang-1, Ang-2)
    • Plasma (EDTA)
  • Custom 2-plex (Eotaxin, Eotaxin-2)
    • Urine
  • Custom 2-plex (IL-5, IL-9)
    • Urine
  • Custom 2-plex (TNFR-1, TNFR-2)
    • Plasma (EDTA)
  • Custom 5-plex (B2M, EGF, NGAL/LCN2, Osteopontin, UMOD)
    • Serum, Plasma (EDTA), Urine
  • Custom 3-plex (Galectin-3,NT-proBNP,ST-2)
    • Serum, Plasma (EDTA)
  • 10-plex Proinflammatory Panel (IL-10, IL-13, IL-1β, IL-2, IL-4, IL-6, IL-8, TNF-α, IFN-γ, IL-12p70)
    • Serum, Plasma (EDTA), Urine
  • 7-plex Angiogenesis Panel (bFGF, Flt-1,PIGF, Tie-2, VEGF, VGEF-C,VGEF-D)
    • Serum, Plasma (EDTA)
  • Custom and preset panels can be customized to individual needs
  • Full list of MESO analytes
    • MESO QuickPlex SQ 120 instrument assays